| IGF-1 | Insulin-like growth factor-1 |
| ADAMTS5 | a disintegrin and metalloproteinase with thrombospondin motifs 5 |
| PG | proteoglycan |
| GAG | glycosaminoglycan |
| NHDFs | normal human dermal fibroblasts |
| DS | dermatan sulfate |
| MMP | matrix metalloproteinase |
| Act D | actinomycin D |
| CHX | cycloheximide |
| rhIGF-1 | recombinant human IGF-1 |
| siRNA | small interference RNA |
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