Figure 2.

Mean number and mean percent of bleeding days with dysmenorrhea (A and B). Mean number and mean percent of nonbleeding days with nonmenstrual pelvic pain (C and D). p < 0.001 (***) and p < 0.01 (**) vs placebo for percent of women with “moderate or severe” or “none” regarding dysmenorrhea or nonmenstrual pelvic pain (NMPP) from a Wilcoxon rank sum test. Number of days is equal to the number of days the subject reported dysmenorrhea or NMPP as none, mild, moderate, or severe. Missing dysmenorrhea with nonmissing NMPP or missing NMPP with nonmissing dysmenorrhea are imputed as zero days. Percentage of days is equal to the number of days the subject reported dysmenorrhea or NMPP divided by the number of days she answered the e-diary, multiplied by 100. Baseline is defined as the average of the last 35 days prior to and including the first dosing date.

Abbreviations: BID, twice daily; QD, once daily.