Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 2;13:913–923. doi: 10.2147/CMAR.S270144

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Zheng et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

The activation of Top2α reduced the anti-cancer effects of si-lncRNA RAMS11 in prostate cancer cells. Top2α protein expressions (A, B), cell proliferation (C), LDH activity cytotoxicity (D), migration rate (E, F), caspase-3/9 activity levels (G), invasion rate (H, I) in vitro model of LNCap cell. *p<0.01 compared with negative group, #p<0.01 compared with down-regulation of RAMS11 group.

Abbreviations: Negative, negative mimics group; SiRAMS11, down-regulation of RAMS11 group; Top2α, over-expression of Top2α group.