Table 26.
Scientific Name | Part Used | Extraction Method, Solvent | Target | Intervention and Duration | Observations | Ref |
---|---|---|---|---|---|---|
Cistus laurifolius | Leaf | Water, ethanol, maceration | Streptozocin diabetic rats | 250, 500 mg/kg | Inhibited of α-glucosidaseand α-amylase | [437] |
Heracleum persicum | Whole plant | Water, maceration | Streptozocin diabetic rats | 100, 200, 400 mg/kg 21 days |
Decreased HbA1c, restored diabetic complications parameters towards normal, increased AST and ALT significantly | [320] |
Juniperus oxycedrus | Berries | Water, maceration isolated compound |
Streptozocin diabetic rats | 500, 1000 mg/kg Shikimic acid: 15 and 30 mg/kg, 8 days |
The effect of shikimic acid was more effective than the reference antidiabetic drug glipizide, TG and enzyme levels were reduced significantly | [438] |
Leaf | Water, ethanol, maceration | Streptozocin diabetic rats | 500, 1000 mg/kg | Fatty acids were found as the major compounds | [440] | |
Fruit, leaf | Ethanol 80%, maceration | Streptozocin diabetic rats | 500, 1000 mg/kg, 10 days | Augment Zn level in liver | [441] | |
Juniperus foetidissima & Juniperus sabina | Leaf, fruit | Ethanol 80%, maceration | Streptozocin diabetic rats | 500, 1000 mg/kg, 8 days | Leaf extract caused death at both doses | [439] |
Origanum minutiflorum | Whole plant | Water, decoction | Streptozocin diabetic rats | 150 mg/kg, 30 days | Decreased ALT and AST levels | [444] |
Salvia triloba | Aerial parts | Methanol 80%, soxhlet | Streptozocin-nicotinamide diabetic rats | 100, 200 mg/kg, 21 days | Little weight loss | [445] |
Thymus praecox | Aerial parts | Methanol, maceration | Streptozocin-nicotinamide diabetic rats | 100, 200 mg/kg, 21 days | Little weight loss | [445] |