Skip to main content
. 2021 Jan 31;22(3):1428. doi: 10.3390/ijms22031428

Figure 6.

Figure 6

Reduced neuraminidase activity in arthritic joints upon zanamivir treatment. (a) 2′-(4-methylumbelliferyl)-α-D-N-acetylneuraminic acid (MUNANA) is catalyzed in the presence of neuraminidase into α-D-N-acetylneuraminic acid and fluorescent 4-methylumbelliferyl. Tissue extracts of CIA hind paws (b) and spleens (c) were prepared and applied to MUNANA assay. Neuraminidase activity was calculated as µU/mg total protein. Results are shown as ± standard deviation (±SD). *** p < 0.005. One-way ANOVA with Tukey’s multiple comparisons test was used for statistical analysis.