Table 3.
Univariate | Multivariate | |||
---|---|---|---|---|
HR(95% CI) | p-Value | HR(95% CI) | p-Value | |
Age | 1.02(0.99–1.05) | 0.31 | ||
Gender (male) | 1.21(0.63–2.32) | 0.57 | ||
Body-mass index (kg/m2) | 1.03(0.94–1.13) | 0.5 | ||
NYHA (I–II vs III–IV) | 2.23(1.01–4.91) | 0.046 | 3.56(1.55–8.14) | 0.003 |
Previous hospitalization for heart Failure | 3.0(1.55–5.82) | 0.001 | 3.41(1.65–7.02) | 0.001 |
Coronary artery disease | 1.75(0.91–3.35) | 0.093 | 1.24(0.58–2.69) | 0.58 |
Ejection fraction ≤ 40% | 1.11(0.58–2.11) | 0.75 | ||
Atrial fibrillation | 1.08(0.54–2.18) | 0.82 | ||
Chronic obstructive pulmonary disease | 1.69(0.80–3.57) | 0.17 | ||
Systolic blood pressure (mmHg) | 1(0.99–1.01) | 0.75 | ||
Log NT-proBNP (pg/mL) | 3.26(1.35–7,87) | 0.009 | 2.8(1.07–7.36) | 0.036 |
Canagliflozin treatment | 0.35(0.17–0.73) | 0.005 | 0.45(0.21–0.96) | 0.039 |