Table 1.

Adverse events during TKI therapy.

	Imatinib	Dasatinib	Nilotinib	Bosutinib	Ponatinib
Fluid retention	+++	−	−	+	−
Muscle cramps	+++	−	−	−	−
Fatigue	++	++	++	++	++
Rash	++	−	+++	+/−	+++
Nausea	++	+/−	+	+++	++
Diarrhea	++	−	−	+++	−
Increased pancreatic enzymes	−	−	++	+	+++
Hypertension	−	++	++	−	+++
Pleural effusion	−	+++	−	+	−
Arterial occlusive events	−	−	++	−	+++

TKI: tyrosine kinase inhibitors; Bold values: most frequent adverse events for each TKI.