Skip to main content
. 2021 Feb 1;26(3):752. doi: 10.3390/molecules26030752

Figure 4.

Figure 4

Chemoprotective and chemotherapeutic mechanisms of SFN in cancer cells. SFN exerts chemoprevention by inducing HO-1 and Phase II enzymes, and increasing GSH concentration expression and activating NK cells, as well as downregulating pro-inflammatory cytokines. In both cases, the effect on immune system is mediated by transcription factors Nrf2 and Nfκβ.