Table 1.

Clinical trials regarding the effect of sulforaphane on immune system (www.clinicaltrials.gov).

Clinical Trial Identifier	Title	Study Population	Duration	Sulforaphane (Dose)	Results	Phase	Status
NCT01357070	Effect of Broccoli Sprout on Blood Levels of Sulforaphane to Reduce Responsiveness of Immune System	6 healthy volunteers, London, United Kingdom	34 months (May 2011–January 2014)	broccoli sprout homogenate (70 g dry weight, orally by three consecutive days).	N.I. 1	N.A. 2	Completed
NCT01183923	Dietary Interventions in Asthma Treatment: Sprouts Study	1 adult, asthmatic, male, white, United States of America	14 months (November 2010–February 2012)	N.I. 1 (broccoli sprouts, one serving per day, 7 days, in a sandwich)	N.I. 1	N.A. 2	Halted
NCT01269723	Effects of Sulforaphane (SFN) on Immune Response to Live Attenuated Influenza Virus in Smokers and Nonsmokers	51 adults, healthy, smokers or nonsmokers, United States of America	28 months (December 2010–March 2013)	N.I.1 (broccoli sprouts homogenate)	N.I. 1	N.A. 2	Completed
NCT01845493	Sulforaphane Supplementation in Atopic Asthmatics (brasma)	16 adults, asthmatics, United States of America	17 months (April 2013–October 2014)	N.I. 1 (broccoli sprouts homogenate orally daily, three days)	N.I. 1	1	Completed
NCT01845220	Prevention of Alcohol Intolerance	30 adults, older adults, sensitive to alcohol on the skin, Japanese, United States of America	27 months (May 2013–July 2015)	150 nmol of sulforaphane/cm2 of skin in 80% acetone	SFN increased erythema (affected skin area) as response to alcohol exposure	2	Completed
NCT02885025	Effects of Broccoli Sprout Extract on Allergy Rhinitis	47 adults, older adults, allergic rhinitis or healthy	18 months (October 2016–March 2019)	N.I. 1 (broccoli sprouts extract)	SFN reduced pro-inflammatory cytokines with and without combination with fluticasone	2	Completed

¹ Not Informed. ² Not Applicable.