aa |
amino acid |
ACT |
adoptive cell therapy |
ADCC |
antibody-dependent cellular cytotoxicity |
APC |
antigen-presenting cells |
APM |
antigen-processing machinery |
β2m |
beta-2 microglobulin |
BTK |
Bruton tyrosine kinase |
CAF |
cancer-associated fibroblast |
CAR |
chimeric antigen receptor |
CSF |
colony-stimulating factor |
CTLA |
cytotoxic T lymphocyte antigen |
DC |
dendritic cells |
ECM |
extracellular matrix |
EMT |
epithelial–mesenchymal transition |
ER |
endoplasmic reticulum |
HC |
heavy chain |
HDAC |
histone deacetylase |
HLA |
human leukocyte antigen |
iCP |
immune checkpoint |
iCPI |
immune checkpoint inhibitors |
IDO |
indoleamine 2,3-dioxygenase |
IFN |
interferon |
IL |
interleukin |
JAK |
janus kinase |
KIR |
killer immunoglobulin receptors |
Lag |
lymphocyte-activation gene |
MDSC |
myeloid-derived suppressor cell |
NK |
natural killer |
NKG2D |
Natural Killer group 2 member D |
PD1 |
programmed cell death 1 |
PD-L1 |
programmed cell death ligand 1 |
PI3K |
phospho-inositol-3-kinase |
PRR |
pattern recognition receptor |
PTEN |
phosphatase and tensin homolog |
STAT |
signal transducer and activator of transcription |
TAA |
tumor-associated antigen |
TAM |
tumor-associated macrophages |
TAN |
tumor-associated neutrophils |
TAP |
transporter associated with antigen processing |
TCR |
T cell receptor |
TGF |
transforming growth factor |
TIGIT |
T-cell immunoreceptor with Ig and ITIM domain |
TIL |
tumor-infiltrating lymphocytes |
TIM-3 |
T-cell immunoglobulin and mucin domain-3 |
TMB |
tumor mutational burden |
TME |
tumor microenvironment |
Treg |
regulatory T cells |
TSA |
tumor-specific antigens |
VEGF |
vascular endothelial growth factor |