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. 2021 Feb 1;13(3):551. doi: 10.3390/cancers13030551
aa amino acid
ACT adoptive cell therapy
ADCC antibody-dependent cellular cytotoxicity
APC antigen-presenting cells
APM antigen-processing machinery
β2m beta-2 microglobulin
BTK Bruton tyrosine kinase
CAF cancer-associated fibroblast
CAR chimeric antigen receptor
CSF colony-stimulating factor
CTLA cytotoxic T lymphocyte antigen
DC dendritic cells
ECM extracellular matrix
EMT epithelial–mesenchymal transition
ER endoplasmic reticulum
HC heavy chain
HDAC histone deacetylase
HLA human leukocyte antigen
iCP immune checkpoint
iCPI immune checkpoint inhibitors
IDO indoleamine 2,3-dioxygenase
IFN interferon
IL interleukin
JAK janus kinase
KIR killer immunoglobulin receptors
Lag lymphocyte-activation gene
MDSC myeloid-derived suppressor cell
NK natural killer
NKG2D Natural Killer group 2 member D
PD1 programmed cell death 1
PD-L1 programmed cell death ligand 1
PI3K phospho-inositol-3-kinase
PRR pattern recognition receptor
PTEN phosphatase and tensin homolog
STAT signal transducer and activator of transcription
TAA tumor-associated antigen
TAM tumor-associated macrophages
TAN tumor-associated neutrophils
TAP transporter associated with antigen processing
TCR T cell receptor
TGF transforming growth factor
TIGIT T-cell immunoreceptor with Ig and ITIM domain
TIL tumor-infiltrating lymphocytes
TIM-3 T-cell immunoglobulin and mucin domain-3
TMB tumor mutational burden
TME tumor microenvironment
Treg regulatory T cells
TSA tumor-specific antigens
VEGF vascular endothelial growth factor