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Comprehensive serum miRNA sequencing in the remission group. (A) Time line chart of the remission group; (B,C) heatmap and principal component analysis of serum miRNA profiles. Blue and red letters indicate responsive (R1–5 and R7) and unresponsive (R8–14) cases, respectively. R6 was excluded because of low read counts; (D,E) Up- and downregulated candidate miRNAs in the remission group. Red lines indicate absolute Log2 fold change of >1, fold change of >2 or <0.5; R, remission.
