Table 2.

Cox regression model analysis for prediction of disease-free survival and recurrence-free survival.

	Disease-Free Survival				Recurrence-Free Survival
	Univariate		Multivariate		Univariate		Multivariate
Clinico-pathological Variables	Risk Ratio (95% CI)	p Value	Risk Ratio (95% CI)	p Value	Risk Ratio (95% CI)	p Value	Risk Ratio (95% CI)	p Value
Age Above ≥55 years (vs. <55 years)	2.54 (2.03–3.16)	<0.0001 *	2.13 (1.59–2.87)	<0.0001 *	2.97 (2.31–3.80)	<0.0001 *	2.65 (1.90–3.70)	<0.0001 *
Sex Male (vs. Female)	0.59 (0.48–0.73)	<0.0001 *	0.67 (0.52–0.86)	0.0016 *	0.56 (0.44–0.71)	<0.0001 *	0.71 (0.53–0.95)	0.0224 *
Histology Tall Cell Variant (vs. Other Variants)	1.94 (1.41–2.61)	<0.0001 *	1.48 (1.04–2.05)	0.0236 *	1.27 (0.84–1.83)	0.2528	0.93 (0.59–1.40)	0.7422
Extrathyroidal Extension Present (vs. Absent)	2.27 (1.82–2.86)	<0.0001 *	1.40 (1.07–1.82)	0.0149 *	2.92 (2.24–3.85)	<0.0001 *	1.72 (1.25–2.36)	0.0008 *
Lymph Node Metastasis N1 (vs. N0)	2.33 (1.84–2.96)	<0.0001 *	1.72 (1.30–2.26)	0.0001 *	2.74 (2.09–3.63)	<0.0001 *	2.31 (1.65–3.23)	<0.0001 *
Distant Metastasis Present (vs. Absent)	3.99 (2.83–5.62)	<0.0001 *	2.29 (1.43–3.69)	0.0006 *	6.14 (4.25–8.62)	<0.0001 *	2.78 (1.68–4.60)	<0.0001 *
Stage IV (vs. I-III)	3.62 (2.39–5.27)	<0.0001 *	0.83 (0.46–1.49)	0.5305	6.25 (4.12–9.10)	<0.0001 *	0.81 (0.44–1.52)	0.5164
PD-L1 High (vs. Low)	2.04 (1.66–2.52)	<0.0001 *	2.08 (1.65–2.62)	<0.0001 *	1.51 (1.19–1.92)	0.0008 *	1.54 (1.18–2.00)	0.0013 *

* Significant p value.