Table 1.
Calculated salt bridge distances formed between CD47/CD47OX and SIRPα systems.
| No. | CD47/CD47OX | SIRPα | N-O Distance Forming Salt Bridge (Å) | |
|---|---|---|---|---|
| Native | Oxidized | |||
| 1 | Glu29 | Arg69 | 6.53 ± 1.74 | 7.60 ± 0.76 |
| 2 | Glu35 | Arg69 | 5.37 ± 3.37 | 2.43 ± 0.33 |
| 3 | Lys39/Ally39 | Asp100 | 3.55 ± 0.82 | — |
| 4 | Lys41/Ally41 | Asp100 | 7.39 ± 1.05 | — |
| 5 | Asp51 | Arg95 | 7.24 ± 1.97 | 7.64 ± 1.06 |
| 6 | Glu97 | Lys53 | 5.64 ± 1.57 | 4.74 ± 167 |
| 7 | Glu97 | Lys96 | 3.88 ± 0.95 | 4.89 ± 1.33 |
| 8 | Glu104 | Lys53 | 5.71 ± 1.29 | 4.82 ± 1.20 |
| 9 | Glu106 | Lys53 | 3.66 ± 0.74 | 4.31 ± 1.03 |
| 10 | Glu106 | Lys96 | 8.13 ± 0.91 | 8.38 ± 1.34 |