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. 2021 Feb 2;13(3):570. doi: 10.3390/cancers13030570

Table 1.

HOTAIR miRNA targets in human cancers.

miRNA ID HOTAIR Role on Expression Tumor Types References
miR-1 suppression Liver cancer, medulloblastoma [108,109]
miR-7 suppression Breast cancer [110]
miR-17-5p suppression Cervical cancer [111]
miR-34a suppression Breast, pancreatic, gastric, prostate, colon cancers [105,106,112,113,114]
miR-101 suppression Head and neck cancer [115]
miR-101-3p inverse suppression Gastric cancer [37]
miR-122 suppression Liver cancer [116]
miR-124 suppression Gastric cancer [113]
miR-130a-5p suppression esophageal squamous cell carcinoma, gall bladder [117]
miR-138-5p suppression Ovarian cancer [118]
miR-141 inverse suppression Kidney cancer, glioma [35,119]
miR-145 suppression Liver cancer [120]
miR-146a-5p inverse suppression Breast cancer [34]
miR-148a suppression Breast, cervical, esophageal squamous cell cancers [121,122,123]
miR-148b-3p suppression Glioma [124]
miR-152 suppression Prostate, gastric cancers [125,126]
miR-193a suppression Prostate cancer, myeloid leukemia [127,128]
miR-200c suppression Ovarian cancer [129]
miR-204 suppression Breast, kidney cancers [130,131]
miR-205 suppression Bladder cancer [24]
miR-206 suppression Breast, colon cancer, ovarian cancer, medulloblastoma [22,23,109,132]
miR-214 suppression Colon cancer [133]
miR-217 suppression Lung, kidney, gastric cancers, osteosarcoma [134,135,136,137]
miR-217-5p suppression Liver cancer [138]
miR-218 suppression Breast, liver cancers [139,140]
miR-326 suppression Lung cancer, colon cancer, glioma [141,142,143,144]
miR-331-3p suppression Gastric cancer [145]
miR-373 suppression Ovarian cancer [146]
miR-449b suppression Breast cancer [147]
miR-454-3p suppression Gastric cancer, chondrosarcoma [148,149]
miR-483-3p suppression Medulloblastoma [150]
miR-545 suppression Colon cancer [151]
miR-613 suppression Pancreatic cancer, retinoblastoma [152,153]
miR-663b suppression Pancreatic cancer [154]