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. 2021 Feb 2;13(3):572. doi: 10.3390/cancers13030572

Table 4.

Multivariate model of SCAs corrected by stage, age, and MNA.

Model Marker EFS OS
HR 95% CL p HR 95% CL p
A SCAs 0.67 0.15−2.91 0.59 1.06 0.16−6.93 0.95
B 1 ploss 0.83 0.19−3.63 0.80 0.38 0.07−1.97 0.25
1 qgain/loss 1.68 0.43−6.53 0.46 2.45 0.56−10.7 0.23
3 ploss 0.95 0.26−3.52 0.94 0.62 0.15−2.66 0.52
11 qloss 1.69 0.46−6.23 0.43 2.08 0.50−8.74 0.32
17 qgain 0.30 0.03−3.52 0.34 2.59 0.26−26.2 0.42

Multivariate analysis (MVA) showing the hazard ratio (HR) with 95% confidence level (CL), event-free survival (EFS), and overall survival (OS) of segmental chromosomal alterations (SCAs). Model A showing MVA of all SCAs combined (including 1ploss, 1qgain/1qloss, 2pgain, 3ploss, 4ploss, 5ploss, 6qloss, 9ploss, 11qloss, 14qloss, 17ploss, 17qgain, 19qloss, and 22qloss). Model B showing MVA of specific SCAs univariately significant for a lower EFS and OS.