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Radiation alters the secretome of normal rectal tissue. NCM from mock-irradiated and irradiated normal rectal biopsies were screened for the secretion of 54 inflammatory proteins using a multiplex ELISA. Following a single fraction of 1.8 Gy radiation, there were significantly higher levels of (A) IL-15 and (B) CCL22 in the normal rectal secretome. All data expressed as mean ± SEM. Statistical analysis by Wilcoxon signed-rank test. n = 8 for CCL22 and n = 7 for IL-15, * p < 0.05.
