Figure 3.

DDMs are effective and robust to quantify spatial distributions. (a) After signal binarize Table 1. removed), area- (Im1, 1-pixel object removal) or connectivity-based denoising (Im2, Im3 and Im4, 4-, diagonal- and full- connectivity-based denoising, respectively). (b) The signal accuracy reduction caused by resolution halving of COL7 to COL7-h is better resisted by our method application, as quantified by a maximum NCC coefficient of 0.79 for COL7 and COL7-h DDMs. The colorbar indicates the normalized function values. Scale bars: 5 µm.