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. 2021 Feb 2;22(3):1501. doi: 10.3390/ijms22031501

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The point graph and heatmap showing the average intensity of proteins creating multisynthetase (A) and ribosome (B) complexes in keratinocytes following UVA (30 J/cm²) or UVB (60 mJ/cm²) radiation and treated with cannabidiol (CBD, 4 μM) in a three-dimensional culture model. Proteins IDs: P07814, glutamate/proline-tRNA ligase; P14868, aspartate-tRNA ligase; P41252, isoleucine-tRNA ligase; P47897, glutamine-tRNA ligase; P54136, arginine-tRNA ligase; P56192, methionine-tRNA ligase; Q15046, lysine-tRNA ligase; Q9P2J5, leucine-tRNA ligase; P62081, P46781, P25398, P60866, 40S ribosomal proteins S7, S9, S12, S20; P39023, P27635, P30050, P35268, P46779, 60S ribosomal protein L3, L10, L12, L22, L28. Statistical significances showed only for the whole complexes. x: statistically significant differences vs. non-treated cells, p < 0.05; y: statistically significant differences vs. CBD-treated cells, p < 0.05; a: statistically significant differences vs. UVA-irradiated cells, p < 0.05; b: statistically significant differences vs. UVB-irradiated cells, p < 0.05.