Table 2.
Correlation of disease severity (β) and Krenn score (α) with expression of iNOS, BCL-2 and MMP-9 in intima and subintima of OA patients.
| Disease Severity | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Control | Moderate OA | Severe OA | |||||||
| α | β | R2 | α | β | R2 | α | β | R2 | |
| Age (years) | |||||||||
| iNOS intima | 0 | 727.3 (692.9–761.6) |
0 | 556.6 (446.2–667) |
3003 (2212–3793) |
98% * | 372.7 (319.3–426.1) |
670.2 (220–1120) |
94% * |
| iNOS subintima | 0 | 59 (49.3–68.7) | 0 | supplementary Figure S1 | 7464 (7023–7904) | 99% * | 67.45 (53.85–81.04) | –154.9 (–269.5–0) | 89% * |
| BCL-2 intima | 0 | 3110 (2769–3451) | 0 | 0 | 3504 (3108–3900) | 0 | 177.2 (56.26–298.1) | 2022 (1003–3041) | 41% * |
| BCL-2 subintima | 0 | 4134 (3845–4423) | 0 | 0 | 4460 (4230–4689) | 0 | 0 | 7194 (6762–7626) | 0 |
| MMP-9 intima | 0 | 261 (234–288) | 0 | 0 | 7223 (7043–7404) | 0 | 0 | 7465 (7292–7638) | 0 |
| MMP-9 subintima | 0 | 33.88 (23.42–44.33) | 0 | 0 | 3252 (2652–3852) | 0 | 0 | 2184 (1304–3065) | 0 |
* ANOVA p value for model < 0.0001; α–slope; β–intercept. Data in the brackets indicate 95% CI of model parameter. Number of examined iNOS, BCL-2 and MMP-9 positive cells are expressed as number of cells/mm2.