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. 2021 Jan 30;2021:1250858. doi: 10.1155/2021/1250858

Figure 3.

Figure 3

Effect of BGP-15 treatment on the phosphorylation of Akt-1Ser473 and GSK-3βSer9. Representative Western blot analysis of Akt-1 and GSK-3β phosphorylation and densitometric evaluation are shown. GAPDH was used as a loading control. WKY: age-matched normotensive Wistar-Kyoto rats, n = 7; SHR-Baseline: 15-month-old spontaneously hypertensive rats, n = 7; SHR-C: nontreated spontaneously hypertensive rats, n = 7; SHR-B: spontaneously hypertensive rats receiving BGP-15 for 18 weeks, n = 7. Values are mean ± SEM. ∗∗p < 0.01 vs. WKY, ##p < 0.01 vs. SHR-Baseline, §p < 0.05 vs. SHR-C, §§p < 0.01 vs. SHR-C.