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. 2021 Jan 30;2021:1250858. doi: 10.1155/2021/1250858

Table 1.

Effect of BGP-15 administration on gravimetric parameters of SHR animals.

WKY (n = 7) SHR-baseline (n = 7) SHR-C (n = 7) SHR-B (n = 7)
BWSTART (g) 386.40 ± 4.33 343.21 ± 2.48∗∗ 346.90 ± 6.65∗∗ 340.73 ± 6.32∗∗
BWEND (g) 401.45 ± 8.94 358.13 ± 5.08∗∗ 356.85 ± 4.54∗∗
HWEND (g) 1.12 ± 0.04 1.16 ± 0.02 1.49 ± 0.05∗∗,## 1.23 ± 0.02§§
VWEND (g) 0.95 ± 0.04 1.09 ± 0.02 1.33 ± 0.05∗∗,## 1.14 ± 0.02§§
VW/BWEND (mg/g) 2.28 ± 0.11 3.19 ± 0.08∗∗ 3.73 ± 0.16∗∗,## 3.21 ± 0.03
VW/TLEND (mg/mm) 21.27 ± 0.79 24.76 ± 0.82 29.79 ± 0.94∗∗,## 25.76 ± 0.46,§§
Lung wet weight/weightEND (g/g) 4.42 ± 0.26 4.51 ± 0.13 5.68 ± 0.24∗∗,## 4.68 ± 0.13§§

BWSTART: body weight at the beginning of the treatment; BWEND: body weight at the end of the treatment; HWEND: heart weight at the end of the treatment; VWEND: ventricles weight at the end of the treatment; TLEND: length of the right tibia at the end of the treatment. Values are means + SEM. WKY: age-matched normotensive Wistar-Kyoto rats, n = 7; SHR-Baseline: 15-month-old spontaneously hypertensive rats, n = 7; SHR-C: nontreated spontaneously hypertensive rats, n = 7; SHR-B: spontaneously hypertensive rats receiving BGP-15 for 18 weeks, n = 7. p < 0.05 vs. WKY, ∗∗p < 0.01 vs. WKY, ##p < 0.01 vs. SHR-Baseline, §p < 0.05 vs. SHR-C, §§p < 0.01 vs. SHR-C.