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20(S)-Rg3降低VHL基因启动子区的甲基化水平
20(S)-Rg3 reduces methylation level in VHL gene promoter.A: Real-time PCR shows increased VHL mRNAlevel in 5-Aza-CdRtreated SKOV3 cells; B: The promoter region of VHL gene is predicted to contain CpG islands; C: MSP results show significantly decreased methylation level in the promoter region of VHL gene by 20(S)-Rg3. U=Unmethylated. M=Methylated. *P < 0.05.
