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. 2020 Oct 19;185(2):293–305. doi: 10.1007/s10549-020-05955-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Patients’ outcomes of Breast cancer survival on Transcriptomic level. a Cumulative survival of BC patients stratified by ISG15 mRNA expression in the METABRIC cohort. b Cumulative survival of BC patients stratified by ISG15 mRNA expression in the KM-Plotter cohort. c Cumulative survival of BC patients ISG15 mRNA expression in the TCGA cohort. d Cumulative survival of BC patients stratified by ISG15 mRNA expression in the METABRIC-restricted LVI-positive cohort. e Cumulative survival of BC patients stratified by ISG15 mRNA expression in the METABRIC-restricted HER2-positive cohort. f Cumulative survival of BC patients stratified by ISG15 mRNA expression in the TCGA-restricted LVI-positive cohort. g Cumulative survival of BC patients stratified by ISG15 mRNA expression in the TCGA-restricted HER2-positive cohort