The recommendation in National Institute for Health and Care Excellence (NICE) Technical Support Document 19 to verify extrapolations resulting from a partitioned survival model by means of a state transition model alongside it is rarely to never brought to practice in a Single Technology Appraisal. It is also not necessarily something that committees appreciate having for making decisions. Reconsideration of this recommendation may be called for.

The use of matching-adjusted indirect comparison (MAIC) remains largely untested, and there is a lack of clarity whether the results are relevant to the decision problem. In particular, unanchored MAICs are regarded as unfeasible.

NICE recommended lenalidomide with rituximab, within its marketing authorisation, as an option for previously treated follicular lymphoma (grade 1–3A) in adults, contingent on the company providing lenalidomide according to the commercial arrangement.