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. 2020 Apr 17;60(1):1–28. doi: 10.1007/s00394-020-02247-8

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Forest plot showing mean difference and 95% confidence intervals for the impact of chronic red wine polyphenol supplementation compared to placebo-controls on diastolic blood pressure in humans, with subgroup analysis based on the health status of the included cohort. Horizontal lines indicate the 95% confidence interval; shaded diamond shows the calculated subgroup and overall mean difference alongside the results of the random effect model for each group