Table 6.

Quality of reporting of published articles assessing the cost effectiveness of drugs for osteoporosis using the ESCEO-IOF osteoporosis specific checklist

Item	Recommendation	Article references
		[12]	[32]	[36]	[17]	[34]	[33]	[21]	[10]	[26]	[25]	[11]	[22]	[31]
Transition probabilities	Report the transition probabilities and how they were estimated (including increased fracture risk)	No	Yes	Yes	No	Yes	Yes	Yes	NA	Yes	Yes	No	Yes	Yes
Excess mortality after fractures	Describe approaches and data sources used for the excess mortality after fractures	No	Yes	Yes	No	No	Yes	Yes	NA	No	Yes	No	Yes	Yes
Fractures costs	Describe approaches and data sources used for fractures costs	Yes	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	Yes	No	Yes	Yes
Fractures effects on utility	Describe approaches and data sources used for the effects of fractures on utility	No	Yes	Yes	No	Yes	Yes	Yes	No	Yes	Yes	No	Yes	Yes
Treatment effect during treatment	Describe fully the methods used for the identification, selection, and synthesis of clinical effectiveness data (per fracture site)	No	Yes	Yes	Yes	Yes	Yes	Yes	No	Yes	Yes	No	Yes	Yes
Treatment effect after discontinuation	Describe fully the methods used for the treatment effect after discontinuation	No	Yes	Yes	No	Yes	Yes	Yes	No	Yes	Yes	No	Yes	Yes
Medication adherence	Describe approaches and data sources used for modeling medication adherence	No	Yes	Yes	No	Yes	No	Yes	No	No	Yes	No	Yes	Yes
Treatment costs	Describe approaches and data sources used for therapy costs	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Part	Yes	Yes	Yes	Yes	Yes
Treatment side effects	Describe approaches and data sources used for costs and utilities effects of adverse events	No	Yes	Yes	No	No	No	No	No	Yes	No	No	No	No
Scoring		2	9	9	3	7	7	8	0.5	7	8	1	8	8

Item	Recommendation	Article references
		[14]	[13]	[18]	[19]	[30]	[35]	[29]	[23]	[24]	[27]	[15]	[28]	[16]	[20]
Transition probabilities	Report the transition probabilities and how they were estimated (including increased fracture risk)	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Excess mortality after fractures	Describe approaches and data sources used for the excess mortality after fractures	Yes	No	Yes	Yes	Yes	Yes	Yes	No	Yes	Yes	Yes	Yes	Yes	Yes
Fracture costs	Describe approaches and data sources used for fracture costs	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Fracture effects on utility	Describe approaches and data sources used for the effects of fractures on utility	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Treatment effect during treatment	Describe fully the methods used for the identification, selection, and synthesis of clinical effectiveness data (per fracture site)	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Treatment effect after discontinuation	Describe fully the methods used for the treatment effect after discontinuation	Yes	No	Yes	Yes	Yes	Yes	Yes	No	No	Yes	No	Yes	Yes	Yes
Medication adherence	Describe approaches and data sources used for modeling medication adherence	Yes	No	Yes	Yes	Yes	Yes	Yes	No	Yes	Yes	No	Yes	Yes	Yes
Treatment costs	Describe approaches and data sources used for therapy costs	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Treatment side effects	Describe approaches and data sources used for costs and utilities effects of adverse events	No	No	No	No	No	No	No	Yes	No	No	No	Yes	Part	No
Scoring		8	5	8	8	8	8	8	6	7	8	6	9	8.5	8

NA not applicable