Skip to main content
. Author manuscript; available in PMC: 2022 Feb 4.
Published in final edited form as: Structure. 2020 Nov 19;29(2):186–195.e6. doi: 10.1016/j.str.2020.11.001

Figure 4. nMS-based screening to capture intact Mfd-TEC assemblies.

Figure 4.

(A) nMS analyses of TECs containing various nucleic acid scaffolds (NAS) incubated with Mfd. The check mark indicates the condition which generated the highest amount of intact Mfd-TEC complexes that did not show evidence for dissociation or transcript cleavage. Refer to Figure S2, Figure S3, and Data S1 for more details. (B) Representative single particle cryo-EM structure of the Mfd-bound TEC containing NAS 3 (PDB ID: 6x5q) (Kang et al., 2020).