Table 2. Interaction analysis between BED and RT + eIT sequencing.

	eIT Before or concomitant to RT (N=817)	eIT after RT (N=1,153)
Median OS (months)
BED <39	6.83	9.20
BED =39	9.63	11.96
BED >39 (excl SRT)	13.47	12.06
SRT	24.87	25.00
HR (95% CI)
BED <39	Ref	0.68 (0.52–0.88)
BED =39	Ref	0.83 (0.72–0.97)
BED >39 (excl SRT)	Ref	1.07 (0.91–1.26)
SRT	Ref	0.90 (0.49–1.66)

BED, biologically effective dose; RT, radiotherapy; eIT, early-incorporation immunotherapy.