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ctDNA clearance at 6 weeks after initiating osimertinib therapy (first follow-up) is associated with significantly longer PFS (A) and OS (B) as compared to patients with detectable ctDNA. Red line represents patients without detectable ctDNA at first follow-up (n=21). Blue line represents patients with detectable ctDNA at first follow-up (n=17). Dotted line indicates the median PFS or OS. The risk table below illustrates the number of patients included per time point.
