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. 2021 Jan;10(1):45–56. doi: 10.21037/tlcr-20-870

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2021 Translational Lung Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Dose-response association between dietary potassium intake (energy-adjusted) and lung cancer risk for females in the WHI cohort (A), females in the PLCO trial (B), the combination of females (C), and males in the PLCO trial (D) using spline smoothed model. Multivariable risk estimate was calculated to adjust all covariates by spline regression with three knots (20th percentiles as the reference, 2,381 mg/day). Blue solid line represented point estimates, dashed lines and shadow area represented 95% confidence intervals. Red solid points and vertical lines represented HRs and 95% CIs of lung cancer based on categories of dietary potassium intake (compared with the lowest quintile), respectively. Black curve showed the kernel density estimates of participants (right y-axis) consuming of potassium.