Table 3. Hazard ratios and 95% confidence intervals of lung cancer based on categories of dietary potassium intake for female.
| Quintile 1 | Quintile 2 | Quintile 3 | Quintile 4 | Quintile 5 | Ptrendc | |
|---|---|---|---|---|---|---|
| Dietary potassium intakea | <2,253.6 | 2,253.6–2,597.5 | 2,597.5–2,906.6 | 2,906.6–3,297.8 | ≥3,297.8 | |
| PLCO (N=48,025) | ||||||
| Cases/person-years | 78/44,846 | 80/60,993 | 108/78,777 | 106/93,023 | 171/113,353 | |
| Multivariable model HRb | 1.00 | 0.87 (0.63, 1.19) | 0.87 (0.65, 1.18) | 0.71 (0.53, 0.97) | 0.87 (0.66, 1.15) | 0.359 |
| WHI (N=72,425) | ||||||
| Cases/person-years | 461/269,115 | 379/256,249 | 342/228,387 | 230/204,040 | 219/165,679 | |
| Multivariable model HRb | 1.00 | 0.94 (0.82, 1.08) | 0.98 (0.85, 1.13) | 0.75 (0.64, 0.89) | 0.90 (0.76, 1.06) | 0.023 |
| ALL (N=120,450) | ||||||
| Cases/person-years | 539/313,961 | 459/317,242 | 450/307,165 | 336/297,063 | 390/279,032 | |
| Multivariable model HRb | 1.00 | 0.93 (0.82, 1.05) | 0.96 (0.84, 1.09) | 0.75 (0.65, 0.86) | 0.90 (0.79, 1.03) | 0.017 |
| Dietary sodium intakea | <2,186.3 | 2,186.3–2,409.5 | 2,409.5–2,610.6 | 2,610.6–2,871.8 | ≥2,871.8 | |
| PLCO (N=48,025) | ||||||
| Cases/person-years | 184/114,533 | 141/103,569 | 101/80,981 | 75/55,696 | 42/36,213 | |
| Multivariable model HRb | 1.00 | 1.01 (0.81, 1.27) | 0.93 (0.72, 1.19) | 0.95 (0.72, 1.25) | 0.76 (0.54, 1.07) | 0.150 |
| WHI (N=72,425) | ||||||
| Cases/person-years | 234/151,282 | 222/175,731 | 333/220,300 | 387/269,553 | 455/306,604 | |
| Multivariable model HRb | 1.00 | 0.91 (0.75, 1.09) | 1.14 (0.96, 1.36) | 1.10 (0.93, 1.30) | 1.12 (0.95, 1.32) | 0.05 |
| ALL (N=120,450) | ||||||
| Cases/person-years | 418/265,815 | 363/279,300 | 434/301,281 | 462/325,249 | 497/342,817 | |
| Multivariable model HRb | 1.00 | 0.92 (0.80, 1.07) | 1.05 (0.91, 1.21) | 1.04 (0.90, 1.19) | 1.04 (0.91, 1.19) | 0.284 |
a, mineral intake was energy-adjusted (mg/day), median intake for continuous and range for quintiles. b, Cox proportional hazard models were used to adjust age, body mass index (kg/m2), energy intake (kcal/day), educational level (3 categories), alcohol consumption (g/day), smoking status (never smokers, former smokers <20 pack-years, former smokers ≥20 pack-years, current smokers <20 pack-years, current smokers ≥20 pack-years), history of diabetes (yes or no), and family history of cancer (yes or no). c, test for linear trend was estimated by assigning the median value of potassium intake in each quintile.