Table 4. Factors associated with improvement rate of pneumonitis.

Variable	Univariate analysis			Multivariable analysis
	OR (95% CI)	P value		OR (95% CI)	P value
Age ≥65 years	3.00 (0.71–12.74)	0.131		1.75 (0.30–10.20)	0.533
Male vs. female	0.69 (0.13–3.73)	0.666		2.43 (0.20–29.69)	0.487
Smoker	0.58 (0.16–2.16)	0.420		0.29 (0.04–3.21)	0.291
Grade 3–5 CIP	0.16 (0.04–0.69)	0.014		0.17 (0.03–0.92)	0.039
Radiotherapy at baseline	0.53 (0.11–2.54)	0.427		0.37(0.04–3.21)	0.367
ICI treatment ≥2nd line	0.25 (0.03–0.99)	0.048		0.40 (0.08–2.06)	0.272
Histology (squamous vs. nonsquamous)	1.48 (0.38–5.73)	0.572		3.17 (0.51–19.65)	0.214

ICI, immune checkpoint inhibitor; CIP, immune checkpoint inhibitor-related pneumonitis; OR, odds ratio; CI, confidence interval.