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. 2021 Jan;9(2):186. doi: 10.21037/atm-20-3814

Table 2. Dose (range) for IT bolus trailing as recommended by PACC (2).

Drug Recommended dose (maximum for naïve patients*)
Morphine 0.1–0.5 mg (0.15 mg)
Hydromorphone 0.025–0.1 mg (0.04 mg)
Fentanyl 15–75 μg (25 μg)
Sufentanil 5–20 μg
Bupivacaine 0.5–2.5 μg
Clonidine 5–20 μg
Ziconotide 1–5 μg

*, starting doses of medication in the opioid-naïve patient for outpatient bolus delivery do not exceed 0.15 mg morphine, 0.04 mg hydromorphone, or 25 μg fentanyl.