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. 2021 Jan;9(2):135. doi: 10.21037/atm-20-7922

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2021 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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The cell cycle pathway showed the most significant upregulation while the cardiac muscle contraction pathway showed the most significant downregulation in EXO1_high breast cancer patients. (A) The pathway mapping plot of cell cycle pathway. The red color indicated up-regulated genes and light green color indicated subpathways of cell cycle pathway; (B) The pathway mapping plot of cardiac muscle contraction pathway. The dark green color indicated down-regulated genes and light green color indicated subpathways of cardiac muscle contraction pathway.