Table 2. Hematological parameters in the iron deficiency anemia (IDA), β-thalassemia trait (β-TT), and α-thalassemia trait (α-TT) groups.
| Parameters | IDA (n=340) | Α-TT (n=66) | Β-TT (n=48) | Kruskal-Wallis test (P) | IDA/α-TT (P) | IDA/β-TT (P) |
|---|---|---|---|---|---|---|
| Age | 29.2±4.1 | 29.5±4.6 | 28.7±4.0 | 0.5797 | – | – |
| Gestational composition ratio | ||||||
| First trimester | 5 (1.5%) | 7 (10.6%) | 4 (8.3%) | <0.01 | <0.025 | <0.025 |
| Second trimester | 70 (20.6%) | 24 (36.4%) | 10 (20.8%) | |||
| Third trimester | 265 (77.9%) | 35 (53.0%) | 34 (70.8%) | |||
| RBC (1012/L) | 4.33±0.43 | 4.60±0.52 | 4.63±0.49 | <0.05 | <0.05& | <0.05& |
| HGB (g/L) | 99 (93.0–104) | 101.00 (95.00–109.75) | 98.00 (91.75–105.25) | <0.05 | <0.05* | 0.823* |
| HCT (%) | 31.75 (30.00–33.10) | 32.75 (30.15–35.30) | 31.75 (30.38–33.38) | <0.05 | <0.05* | 0.671* |
| MCV (fL) | 72.60 (69.20–78.20) | 70.85 (67.80–73.40) | 68.75 (66.65–71.33) | <0.05 | <0.05* | <0.05* |
| MCH (pg) | 22.45 (21.40–23.93) | 22.10 (21.03–23.10) | 21.40 (20.78–21.93) | <0.05 | <0.05* | <0.05* |
| MCHC (%) | 311.00 (305.00–315.00) | 312.50 (307.00–317.75) | 310.50 (305.00–315.25) | 0.447 | – | – |
| RDW-CV (%) | 14.70 (14.00–15.90) | 14.45 (13.90–15.50) | 15.20 (14.80–15.90) | <0.05 | 0.355* | 0.002* |
| RDW-SD | 38.65 (35.60–43.23) | 37.15 (35.60–40.00) | 37.20 (35.98–38.85) | 0.156 | – | – |
| Ret# (109/L) | 2.14 (1.85–2.49) | 2.13 (1.78–2.61) | 2.56 (2.09–3.05) | <0.05 | 0.848* | <0.05* |
| Ret% (%) | 0.09 (0.08–0.11) | 0.10 (0.08–0.12) | 0.12 (0.10–0.14) | <0.05 | <0.05* | <0.05* |
| RPI | 0.90 (0.80–1.10) | 1.00 (0.80–1.30) | 1.10 (0.90–1.30) | <0.05 | <0.05* | <0.05* |
| %MICROr (%) | 13.99 (8.67–26.29) | 7.58 (4.11–11.27) | 12.42 (8.32–18.52) | <0.05 | <0.05* | 0.200* |
| MCVm (fL) | 65.69 (61.85–70.78) | 64.76 (60.48–67.63) | 62.75 (60.28–64.90) | <0.05 | 0.061* | <0.05* |
Data are presented as the mean ± SD or median with the interquartile range in parentheses. P values were assessed using the Kruskal-Wallis test (#), independent samples t-test (&), or Mann-Whitney U test (*). #P<0.05 by Kruskal-Wallis test. *P<0.05 by Mann-Whitney U test. &P<0.05 by independent samples t-test. RBC, red blood cell; HGB, hemoglobin concentration; HCT, hematocrit; HGB, hemoglobin; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; RDW-CV, red blood cell distribution width coefficient of variation; RDW-SD, red blood cell width standard deviation; Ret#, reticulocyte number; Ret%, reticulocyte percentage; RPI, reticulocyte production index; %MICROr, the proportion of reticulocytes less than 60 fl in volume; MCVm, mean corpuscular volume of mature red blood cells.