Table 2. The association between eGFR* levels and the demographic, clinical features, and risk factors of the COVID-19 patients.
| Characteristic, n (%) unless specified otherwise | Normal 135 (54.7) |
Mild 78 (31.6) |
Moderate 23 (9.3) |
Severe 11 (4.5) |
p-value |
|---|---|---|---|---|---|
| Demographic | |||||
| Age, mean ± SD, years | 40.2 ± 12.6 | 50.3 ± 14.0 | 58.3 ± 14.2 | 62.5 ± 8.9 | < 0.001 |
| Male, gender | 96 (71.1) | 60 (76.9) | 22 (95.7) | 11 (100) | 0.016 |
| Time from symptom onset to admission, mean ± SD, days | 5.7 ± 3.0 | 5.7 ± 2.9 | 5.7 ± 3.4 | 5.3 ± 3.3 | 0.981 |
| Clinical presentation | |||||
| Fever | 79 (58.5) | 50 (64.1) | 16 (69.6) | 7 (63.6) | 0.710 |
| Cough | 62 (45.9) | 47 (60.3) | 12 (52.2) | 8 (72.7) | 0.260 |
| Shortness of breath | 47 (34.8) | 27 (34.6) | 10 (43.5) | 5 (45.5) | 0.800 |
| Comorbidities | 54 (40.0) | 39 (50.0) | 21 (91.3) | 10 (90.9) | < 0.001 |
| Risk factors | |||||
| Cardiovascular disease | 3 (2.2) | 3 (3.8) | 1 (4.3) | 1 (9.1) | 0.600 |
| Diabetes mellitus | 29 (21.5) | 22 (28.2) | 18 (78.3) | 8 (72.7) | < 0.001 |
| Hypertension | 34 (25.2) | 21 (26.9) | 13 (56.5) | 8 (72.7) | 0.003 |
| Chronic lung diseases | 4 (3.0) | 5 (6.4) | 0 (0.0) | 0 (0.0) | 0.367 |
| Chronic kidney disease | 0 (0.0) | 0 (0.0) | 2 (8.7) | 2 (18.2) | 0.001 |
| Disease severity | |||||
| Mild-moderate | 78 (57.8) | 38 (48.7) | 7 (30.4) | 0 (0.0) | |
| Severe | 35 (25.9) | 22 (28.2) | 4 (17.4) | 4 (36.4) | < 0.001 |
| Critical | 22 (16.3) | 18 (23.1) | 12 (52.2) | 7 (63.6) | |
| ICU admission | 22 (16.3) | 18 (23.1) | 12 (52.2) | 8 (72.7) | < 0.001 |
eGFR: estimated glomerular filtration rate; SD: standard deviation; ICU: intensive care unit.
*Three cases (out of the 250) had missing serum creatinine levels and they were not included in the eGFR calculations.