Table 4.

Univariable and multivariate analysis for CLNM.

	Univariate analysis			Multivariate analysis
Risk factors	CLNM+	CLNM−	P value	P value	OR (95% CI)
Age at diagnosis (years)			<0.001	<0.001	2.187 (1.606–2.978)
<55	372	444
≥55	81	210
Gender			0.012	0.005	0.651 (0.484–0.876)
Female	321	507
Male	132	147
Tumor size (mm)			<0.001
≤5	108	276		<0.001
>5, ≤10	135	231		<0.001	3.415 (1.896–6.150)
>10, ≤20	168	126		<0.001	2.887 (1.614–5.162)
>20	42	21		0.261	1.403 (0.777–2.533)
Multifocal neoplasms			0.004	0.600
Positive	111	114
Negative	342	540
Bilateral neoplasms			0.062
Positive	81	90
Negative	372	564
Extrathyroidal extension			<0.001	0.617
Positive	66	54
Negative	387	600
Hashimoto thyroiditis			0.247
Positive	87	108
Negative	366	546

CLNM: central lymph node metastasis.