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. 2021 Jan 25;11:601513. doi: 10.3389/fphar.2020.601513

TABLE 3.

Adverse events.

GNRI<92 (n = 45) GNRI>92 (n = 125) p value
n % n %
Neutropenia 0.028*
Grade 1/2 4 (8.89%) 30 (24.00%)
Grade 3/4 15 (33.33%) 48 (38.40%)
Febrile neutropenia 0.001**
Grade 3/4 16 (35.56%) 15 (12.00%)
Rash a 0.683
Grade 1/2 1 (2.22%) 7 (5.60%)
Fatigue 0.086
Grade 1/2 11 (24.44%) 14 (11.20%)
Grade 3/4 0 (0.00%) 1 (0.80%)
Elevated AST/ALT a 0.006**
Grade 1/2 8 (17.78%) 5 (4.00%)
Diarrhea a 0.286
Grade 1/2 2 (4.44%) 2 (1.60%)
Nausea 0.247
Grade 1/2 6 (13.33%) 17 (13.60%)
Grade 3/4 1 (2.22%) 0 (0.00%)

Chi-Square test.

a

Fisher's Exact test. *p< 0.05, **p< 0.01.

GNRI, Geriatric Nutritional Risk Index; AST, Aspartate aminotransferase; ALT, Alanine aminotransferase.