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. 2021 Jan 25;11:588259. doi: 10.3389/fphar.2020.588259

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Copyright © 2021 Zhang, Li, Ma, Liu, Wang, Zhang, Li, Li and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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RRP affects the development of atherosclerosis. (A) Representative Oil-red O staining of the entire aorta. (B) Representative images of H&E, Masson, and Movat staining of the aortic root (magnification, ×50). (C) Quantification of the en face lesion area of the entire aorta. (D) Percentage of aortic plaque area. (E) Percentage of collagen fiber content. (F) Percentage of elastin plaque area (elastin per plaque). The data are expressed as the mean ± SD, n = 6 for each group. ∗p < 0.05 vs. the model group.