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. 2021 Jan 25;11:626013. doi: 10.3389/fneur.2020.626013

Table 3.

Functional enrichment analysis of differentially expressed genes in the module.

Category Term P-value Genes
KEGG_PATHWAY Oxidative phosphorylation 4.47E-06 NDUFA5, UQCR10, NDUFS5, ND4, ATP5I
KEGG_PATHWAY Parkinson's disease 2.84E-04 NDUFA5, UQCR10, NDUFS5, ND4
KEGG_PATHWAY Ribosome 0.007635 RPS17, RPS14, RPL23A
KEGG_PATHWAY Non-alcoholic fatty liver disease (NAFLD) 0.00935 NDUFA5, UQCR10, NDUFS5
KEGG_PATHWAY Alzheimer's disease 0.011486 NDUFA5, UQCR10, NDUFS5
KEGG_PATHWAY Huntington's disease 0.014838 NDUFA5, UQCR10, NDUFS5
KEGG_PATHWAY Metabolic pathways 0.021831 NDUFA5, UQCR10, NDUFS5, ND4, ATP5I
GOTERM_BP Mitochondrial electron transport, NADH to ubiquinone 2.96E-04 NDUFA5, NDUFS5, ND4
GOTERM_BP Mitochondrial respiratory chain complex I assembly 4.90E-04 NDUFA5, NDUFS5, ND4
GOTERM_BP SRP-dependent co-translational protein targeting to membrane 0.001088 RPS17, RPS14, RPL23A
GOTERM_BP Viral transcription 0.001539 RPS17, RPS14, RPL23A
GOTERM_BP Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 0.001735 RPS17, RPS14, RPL23A
GOTERM_BP Translational initiation 0.002291 RPS17, RPS14, RPL23A
GOTERM_BP rRNA processing 0.005487 RPS17, RPS14, RPL23A
GOTERM_BP Translation 0.007591 RPS17, RPS14, RPL23A
GOTERM_BP Ribosomal small subunit assembly 0.01014 RPS17, RPS14
GOTERM_CC Mitochondrial inner membrane 2.19E-05 NDUFA5, UQCR10, NDUFS5, ND4, ATP5I
GOTERM_CC Mitochondrial respiratory chain complex I 1.96E-04 NDUFA5, NDUFS5, ND4
GOTERM_CC Ribosome 0.002228 RPS17, RPS14, RPL23A
GOTERM_CC Mitochondrion 0.016474 NDUFS5, ND4, RPS14, ATP5I
GOTERM_CC Cytosolic small ribosomal subunit 0.020882 RPS17, RPS14
GOTERM_MF NADH dehydrogenase (ubiquinone) activity 2.81E-04 NDUFA5, NDUFS5, ND4
GOTERM_MF Structural constituent of ribosome 0.005832 RPS17, RPS14, RPL23A