Table 1.
Baseline characteristics of AIS patients with favorable or unfavorable outcomes.
| Characteristics | Total | The prognosis of 3 months | ||
|---|---|---|---|---|
| Favorable outcomes (n = 318) | Unfavorable outcomes (n = 130) | P-value | ||
| Age (years) | 66.8 ± 12.2 | 64.9 ± 12.1 | 71.5 ± 11.0 | <0.001a |
| Male (n) | 290 (64.7) | 211 (66.4) | 79 (60.8) | 0.262c |
| SBP (mmHg) | 153.7 ± 22.8 | 153.2 ± 23.4 | 154.9 ± 21.4 | 0.469a |
| DBP (mmHg) | 82.0 ± 12.8 | 82.3 ± 13.1 | 81.2 ± 12.1 | 0.433a |
| Admission to hospital (d) | 2.0 (1.0–3.0) | 2.0 (1.0–3.0) | 2.0 (1.0–3.0) | 0.925b |
| Smoking (n) | 193 (43.1) | 146 (45.9) | 57 (48.9) | 0.690c |
| Alcohol drinking (n) | 127 (28.3) | 98 (30.8) | 29 (22.3) | 0.145c |
| NIHSS score on admission | 4.0 (2.0–5.0) | 3.0 (1.0–4.0) | 7.0 (4.0–10.0) | <0.001b |
| Comorbidities | ||||
| Hypertension (n) | 367 (81.9) | 253 (79.6) | 114 (87.7) | 0.042c |
| Diabetes (n) | 172 (38.4) | 119 (37.4) | 53 (40.8) | 0.508c |
| Dyslipidemia (n) | 174 (38.8) | 131 (41.2) | 43 (33.1) | 0.110c |
| Atrial fibrillation (n) | 53 (11.8) | 27 (8.5) | 26 (20.0) | 0.001c |
| Stroke etiologic subtypes | 0.001c | |||
| Large-artery atherosclerosis (n) | 292 (65.2) | 209 (65.7) | 83 (63.9) | |
| Cardioembolic (n) | 57 (12.7) | 31 (9.8) | 26 (20.0) | |
| Small-vessel disease (n) | 53 (11.8) | 47 (14.8) | 6 (4.6) | |
| Other or unknown cause (n) | 46 (10.3) | 31 (9.8) | 15 (11.5) | |
| Laboratory findings | ||||
| WBC (109/L) | 6.9 (5.7–8.2) | 6.6 (5.5–7.8) | 7.6 (6.2–9.3) | <0.001b |
| Neutrophils (109/L) | 4.3 (3.3–5.7) | 4.0 (3.2–4.9) | 5.6 (4.3–7.2) | <0.001b |
| Lymphocytes (109/L) | 1.7 ± 0.7 | 1.8 ± 0.7 | 1.4 ± 0.6 | <0.001a |
| Platelets (109/L) | 225.1 ± 65.3 | 221.3 ± 57.4 | 234.6 ± 81.0 | 0.090a |
| NLR | 2.6 (1.8–4.1) | 2.3 (1.7–3.2) | 4.3 (2.9–6.2) | <0.001b |
| PLR | 134.6 (103.2–185.9) | 123.4 (96.4–166.3) | 173.8 (126.1–242.7) | <0.001b |
| TC (mmol/L) | 4.4 (3.7–5.1) | 4.5 (3.8–5.3) | 4.4 (3.6–4.9) | 0.134b |
| TG (mmol/L) | 1.5 (1.2–2.1) | 1.6 (1.2–2.3) | 1.5 (1.1–1.8) | 0.127b |
| HDL (mmol/L) | 1.0 (0.9–1.2) | 1.0 (0.9–1.2) | 1.0 (0.9–1.2) | 0.800b |
| LDL (mmol/L) | 2.6 ± 0.8 | 2.6 ± 0.8 | 2.5 ± 0.7 | 0.128a |
| SCr (μmol/L) | 71.0 (59.0–84.5) | 71.0 (58.0–85.0) | 70.0 (59.3–84.0) | 0.914b |
| BUN (mmol/L) | 5.1 (4.1–6.4) | 4.9 (4.1–6.1) | 5.7 (4.3–7.3) | <0.001b |
| UA (mmol/L) | 290.5 (232.5–352.0) | 294.0 (240.5–352.5) | 282.0 (208.0–352.0) | 0.256b |
| HCY (mmol/L) | 11.0 (9.0–14.0) | 11.0 (9.0–13.0) | 11.5 (8.0–15.0) | 0.383b |
| FBG (mmol/L) | 5.3 (4.6–6.8) | 5.2 (4.5–6.7) | 5.4 (4.7–7.1) | 0.083b |
| PBG (mmol/L) | 8.1 (6.3–11.5) | 8.2 (6.4–11.7) | 8.0 (6.3–11.3) | 0.790b |
| HbA1c (%) | 6.0 (5.6–7.1) | 6.0 (5.6–7.3) | 6.0 (5.5–6.6) | 0.800b |
| Medications | ||||
| Antiplatelet agents (n) | 341 (76.1) | 248 (78.0) | 93 (71.5) | 0.146c |
| Anticoagulation agents (n) | 40 (8.9) | 19 (6.0) | 21 (16.2) | 0.010c |
| Statin (n) | 349 (77.9) | 245 (77.0) | 104 (80.0) | 0.494c |
SBP, systolic blood pressure; DBP, diastolic blood pressure; WBC, white blood cell; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; TC, total cholesterol; TG, triglycerides; HDL, high-density lipoprotein; LDL, low density lipoprotein; SCr, serum creatinine; BUN, blood urea nitrogen; UA, uric acid; HCY, homocysteine; FBG, fasting blood glucose; PBG, postprandial blood glucose; HbA1C, glycated hemoglobin.
Data are presented as means ± standard deviations and medians (interquartile ranges) or as counts (percentages).
a
Two independent samples t-test.
b
Mann-Whitney U-test.
c
Chi-square test.