Table 3.

Joint effects of NLR and PLR on unfavorable outcomes related acute ischemic stroke.

NLR≥3.51	PLR≥141.52	N	Unfavorable outcomes, # (%)	Crude		Adjusted
				HR (95% CI)	P-value	HR (95% CI)	P-value
Yes	Yes	117	74 (63.25)	Ref	Ref	3.77 (2.38–5.95)	<0.001
Yes	No	25	10 (40.00)	0.61 (0.32, 1.18)	0.141	2.32 (1.10–4.87)	0.027
No	Yes	91	16 (17.58)	0.26 (0.15, 0.44)	<0.001	1.42 (0.75–2.70)	0.285
No	No	215	30 (13.95)	0.22 (0.15, 0.34)	<0.001	Ref	Ref
Interaction of NLR and PLR				1.43 (0.58, 3.50)	0.436	0.71 (0.46, 1.09)	0.114
RERI (95% CI) = 0.27 (−0.22, 0.77)
The synergy index S = 0.73 (0.45, 1.19)

Adjusted for age, hypertension, atrial fibrillation, NIHSS score on admission, stroke etiologic subtypes, FBG, BUN, anticoagulation agents.