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. 2021 Jan 25;12:606927. doi: 10.3389/fnagi.2020.606927

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Copyright © 2021 Jiang, Ma, Wang, Wang, Yang, Li and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PNU-282987 attenuates the 6-OHDA-mediated loss of dopaminergic cells in the left side of SN. The images illustrate the SN immunostained with TH and a nuclear counterstain with hematoxylin staining. Scale bar indicates 200 μm. (A) 6-OHDA-lesion group; (B) 6-OHDA-lesion + sham group; (C) 6-OHDA-lesion + PNU-282987 group. (D) The percentages of TH-positive cells on the damaged side of the SN/cells on the contralateral side among three groups. ⁺p < 0.05 compared with the 6-OHDA-lesion group (n = 6 per group), and *p < 0.05 compared with the 6-OHDA-lesion + sham group (n = 6 per group).