TABLE 1.

The description of different stress in CUMS design.

No	Stress	Description
1	Damp bedding	damp bedding for 24 h
2	Cage tilting	Cage tilting (45°) for 24 h
3	Day–night reversal	Reversal of light/dark cycle for 24 h
4	Food deprivation	Food deprivation for 24 h
5	Water deprivation	Water deprivation for 24 h
6	Restraint	Forced physical restraint for 2 h
7	Swimming	Swimming for 6 min in 4 °C cold water
8	Horizontal oscillation	Horizontal oscillation for 5 min
9	Tail suspension	Tail suspension for 6 min