Table 2.
Glycemic Outcomes for N = 1,435 Study Participants (at Time point 1 vs. Time point 2). Nighttime Is Defined as 10 PM to 6 AM
| Time point 1 | Time point 2 | P | |
|---|---|---|---|
| Time in range (mean) | 76.7 (±11.6) | 77.2 (±12.3) | <0.001 |
| Time in range (median) | 78.2 (70.2–85.1) | 79.2 (70.3–86.2) | <0.001 |
| Time in range at day (mean) | 75.9 (±11.9) | 76.6 (±12.4) | <0.001 |
| Time in range at day (median) | 77.6 (69.2–84.8) | 78.2 (69.2–85.7) | <0.001 |
| Time in range at night (mean) | 78.4 (±13.5) | 78.5 (±14.7) | 0.082 |
| Time in range at night (median) | 80.7 (71.2–88.2) | 82.2 (71.2–89.2) | 0.082 |
| Mean glucose | 147.3 (±18.5) | 146.6 (±19.9) | <0.001 |
| Median glucose | 145.0 (135.0–157.0) | 144.0 (133.0–157.0) | <0.001 |
| Coefficient of variation | 31.8 (±5.2) | 31.3 (±5.2) | <0.001 |
| Time <70 mg/dL | 1.3 (0.6–2.3) | 1.2 (0.5–2.4) | 0.818 |
| Time <54 mg/dL | 0.2 (0.1–0.4) | 0.2 (0.0–0.4) | 0.826 |
| Time >180 mg/dL | 19.8 (12.8–28.4) | 19.0 (11.8–28.2) | <0.001 |
| Time >250 mg/dL | 2.9 (1.2–6.2) | 2.5 (0.9–5.9) | <0.001 |
| Total dose delivered | 45.9 (33.7–64.4) | 45.0 (33.7–63.5) | 0.083 |
| Basal insulin units | 22.5 (15.9–32.3) | 22.6 (16.1–32.8) | <0.001 |
| Bolus insulin units | 22.3 (15.8–32.6) | 21.9 (15.5–32.3) | <0.001 |
| Time in automation | 95.7 (92.7–97.3) | 96.0 (92.6–97.4) | 0.722 |
| Time in sleep activity | 32.8 (27.8–37.1) | 33.4 (27.2–37.6) | <0.001 |
| Time in exercise activity | 0.3 (0.0–2.2) | 0.0 (0.0–2.5) | <0.05 |