Figure 2. Temporal changes of renal and inflammation indices in COVID-19 patients with or without coagulopathy after DIC occurrence. Figure 2 shows dynamic changes of biomarkers of kidney functions and inflammation, including blood urea nitrogen (A), creatinine (B), and high sensitivity C-reactive protein (C) in 198 patients (133 non-coagulopathy patients, 36 non-overt patients and 29 overt-DIC patients) from the day of coagulopathy onset (for coagulopathy patients) or the day of admission (for non-coagulopathy) to discharged or died. *P < 0.05 for overt DIC patients vs non-coagulopathy patients; ^#P < 0.05 for non-overt DIC patients vs non-coagulopathy patients. BUN=blood urea nitrogen, CREA=creatinine, CRP=high sensitivity C-reactive protein.