Table 6.

Multivariate logistic analysis to identify independent variables affecting seizure worsening (N = 151)

Variables	AOR (95%CI)	p value
Occupation
Full-time job	0.61(0.15–2.47)	0.739
Part-time job	0.33 (0.05–2.13)	0.423
Student	0.56 (0.15–2.05)	0372
Not working/retired	1.78 (1.25–2.54)	0. 0018*
Other treatment modalities
VNS	2.54 (0.47–13.68)	0.006*
Time of the last seizure before the pandemic
Less than 3 months	0.22 (0.10–0.50)	0.068
More than 3 months	0
Last medical review before the pandemic
Less than 3 months	0.96 (0.34–2.72)	0.166
Three months or earlier	0
Shortage of ASMs	0.17 (0.22- 1.34)	0.09
Depression during the pandemic
No depression	3.13 (0.81–12.02)	0.10
Mild depression	0.97 (0.24–4.00)	0.97
Moderate depression	1.33 (0.31–5.67)	0.70
Severe depression	0.93 (0.27–3.18)	0.91
Extremely severe depression	0
Impaired sleep during the pandemic	2.89 (1.25–6.70)	0.013*
Stress during the pandemic
No feeling of stress	2.80 (0.90–8.70)	0.75
A mild feeling of stress	1.75 (0.55–5.61)	0.35
A moderate feeling of stress	1.01 (0.72–1.81)	0.045*
A severe feeling of stress	1.66 (1.20–2027)	0.009*
Extremely feeling of stress	0
The concern during the pandemic
Shortage of medications	3.87 (1.37–9.09)	0.001*
To get Coronavirus infections	3.08 (1.23–7.73)	0.001*
Seizure worsening	1.19 (0.41–2.41)	0.001*

AOR Adjusted odds ratio, CI confidence interval

*Statistically significant at p ≤ 0.05