Table 1. Liver biopsy findings in celiac disease patients with elevated aminotransferases.
Study | Patients | Histologic findings on liver biopsy | Biopsies | AILD* |
---|---|---|---|---|
Vajro et al.15 | 6 | Reactive hepatitis | 2 | (−) |
Chronic persistent hepatitis | 2 | |||
Chronic active hepatitis | 2 | |||
Volta et al.18 | 5 | Reactive hepatitis peri-portal inflammation | 2 | (−) |
Mild fatty infiltration | 1 | |||
Bardella et al.19 | 13 | Minimal changes | 9 | (−) |
Fatty infiltration | 3 | |||
Bardella et al.20 | 67 | Chronic active hepatitis | 5 | (−) |
Fatty infiltration | 2 | |||
Hagander et al.21 | 74 | Reactive hepatitis | 5 | N/A |
Hepatic injury | 7 | |||
Jacobsen et al.22 | 62 | Nonspecific hepatitis | 25 | (−) |
Chronic active hepatitis | 5 | |||
Kaukinen et al.23 | 4 | Acute fulminant hepatitis | 1 | N/A |
Congenital liver fibrosis | 1 | |||
Cirrhotic changes | 1 | |||
Mounajjed et al.14 | 26 | Nonspecific findings | 5 | N/A |
Abbreviations: AILD, autoimmune liver disease; N/A, not applicable.
*Serology for autoimmune liver disease; (−), negative serology; N/A, serology not mentioned or not performed.