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. 2021 Feb 3;14:379–389. doi: 10.2147/RMHP.S284473

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© 2021 Asrani et al.

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Method-based categorization of diagnostic approaches in SARS-CoV-2 detection. The current advances in the diagnostic tools for COVID-19 has been revolving around five major technology-based approaches. Serological methods are based upon serum testing that identifies either host antibodies or viral-specific proteins after a patient has been exposed to the virus. Molecular approaches focus upon detection of viral-specific sequence in the patient’s respiratory specimens. Various kits and devices (lab based and POC) have been approved based upon principles of molecular or serological detection. Radiology identifies the clinical changes within the respiratory tracts of the patients using medical imaging such as chest X ray and CT scan. Isolation of virus culture and growth on cell lines is a part of cell culture technique for detection of virus particles.