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. 2021 Jan 21;41:101873. doi: 10.1016/j.redox.2021.101873

Fig. 6.

Fig. 6

Effects of HOCl and co-treatments with SCN−, SeCN−and SeMet on inflammatory gene expression. HCASMC were exposed to 50 μM HOCl (black bars) with addition of 100 μM SCN− (grey bars) or SeCN− (dashed bars) or SeMet (white bars) for 15 min, before re-incubation in cell media for 24 h. Graphs show the mRNA expression of a range of inflammatory genes analyzed by qPCR and normalized to the housekeeping genes 18S and B2M. The data for 2 individual donors 1596 (A) and 1559 (B) are shown separately. Results represent the mean ± SD of 3 replicates and are expressed as an increase compared to (ct) the non-treated control. *p < 0.05, **p < 0.01 and ****p < 0.0001 indicate a significant increase compared to non-treated control, with ##p < 0.01, ###p < 0.001 and ####p < 0.0001 indicating a significance difference compared to HOCl treatment using two-way ANOVA with Dunnett's multiple comparisons post hoc test.